For a long time, people always hope to have a drug that ate after gall-stone can be melt, so that it can be removed from operation of fear and pain.
The 60s of this century, through the mechanism of cholesterol dissolved in the bile of thorough research, people realize that cholesterol can dissolve into the bile, mainly depends on bile; there are a certain amount of phosphorus and bile acid inIf increased cholesterol levels in bile or bile acid content decreases, and will make part of cholesterol can't dissolve in bile precipitation and crystallization, stone formation in the end.Because the cause of formation of cholesterol calculus study this important discovery, imagine if can improve the ability of bile acid dissolve cholesterol, this will make the crystallization precipitation have occurred, even have stone formation of cholesterol to dissolve in the bile.
After a series of experiments and clinical observation research, found that chenodeoxycholic acid can increase the content of bile acid in the bile, improve the ability of biliary cholesterol dissolved, after a long-term medication, can play a part of the cholesterol stone was reduced, or even disappear.Then these one hundred and twenty years, the above two drugs is quickly becoming commonly used therapeutic agents in the treatment of gallstones, are all the rage in western society.

Dosage of chenodeoxycholic acid is one of the world, one of the largest drug for gallstones and synthetic bear bile acid (UDCA) to oxygen and other steroid compound materials.