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The experimental results show that the process is feasible to extract chenodeoxycholic acid from chicken bile. The extraction rate of crude chenodeoxycholic acid from chicken bile can reach more than 0.7%, and the content of chenodeoxycholic acid in crude product is more than 80%. If further improvement of the overall experimental program, to further improve the chicken bile degreasing technology, bile pigment, cholesterol and other substances in the technology, and further reduce the effective component of chenodeoxycholic acid in the whole process of loss, will hope to make crude. The extraction rate of chenodeoxycholic acid is further increased to more than 0.8%, and the content of chenodeoxycholic acid in crude product is more than 90%.
In this study, the synthesis of ursodeoxycholic acid from chenodeoxycholic acid is the original synthesis route is simplified and improved. The new synthetic route can make the comprehensive conversion rate of ursodeoxycholic acid from the original synthetic route about 50% increase to more than 65%. The overall conversion of ursodeoxycholic acid can be further enhanced by further optimization of the hydrogenation catalyst and optimization of the hydrogenation reaction conditions.

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