The effects of dietary chenodeoxycholic acid(CDCA) on fat metabolism, performance and progeny muscle development were discussed. A total of 80 chickens were randomly divided into 5 groups (16 replicates, 1 chick each). The control group was fed with basal diet, and 10, 50, 100 and 500 mg /kg CDCA were added to the basal diet. The test period was 4 weeks. The eggs were collected for the last week of the experiment, and the offspring were divided into five groups according to the group of chickens. The feeding period was 12 weeks.
The results show:
1) The addition of CDCA in the diet had no significant effect on the body weight, egg production rate and egg quality of the chickens (P> 0.05). Compared with the control group, the addition of 100 mg / kg CDCA in the diet could be significantly increased (P <0.05), and significantly reduced the content of very low density lipoprotein (VLDL) in serum (P <0.05). Compared with the control group, the contents of triglyceride (TG) 100 mg / kg CDCA significantly reduced the total bile acid (TBA) content in eggs (P <0.05) on day 14 and day 28, significantly increased intracellular cholesterol (TC) and low density lipoprotein cholesterol LDLC) (P <0.05).
2) Compared with the control group, the addition of 50 mg / kg chenodeoxycholic acid in the diet could significantly increase the muscle density of the offspring muscle and the liver rate of the offspring (P <0.05). The addition of 100 mg / kg CDCA in the diet (LDH) activity in the gastrocnemius muscle of offspring, and 500 mg / kg of diets in the offspring were significantly lower than those in the control group (P <0.05) CDH can significantly reduce the activity of succinate dehydrogenase (SDH) and the LDH activity in the offspring of the offspring (P <0.05). It can be seen that the addition of CDCA to the diet has no significant effect on the performance of the breeder, but it affects the lipid metabolism of the breeder and the deposition of the egg, especially the TBA, and thus inhibit the development of the offspring. The application of poultry diet should pay attention to the dosage and the use of time.